Conjugates were found to possess good powder flow and tabletting properties. Fast disintegrating tablets of domperidone were prepared using corn starch and corn Starch-Neusilin UFL2 conjugates as tablet superdisintegrants in different concentrations. Heckel and Kawakita models were applied to carry out compression studies for the prepared conjugates.
The conjugates were characterized by ATR-FTIR, XRD, DSC, and SEM techniques.
Various powder tests, namely, angle of repose, bulk density, tapped density, Hausner's ratio, Carr's index, swelling index, and powder porosity were conducted on the samples. In the present study, corn Starch-Neusilin UFL2 conjugates were prepared by physical, chemical, and microwave methods with the aim of using the conjugates as tablet superdisintegrant.